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RTEL1 contributes to DNA replication and repair and telomere maintenance

Telomere maintenance and DNA repair are important processes that protect the genome against instability. mRtel1, an essential helicase, is a dominant factor setting telomere length in mice. In addition, mRtel1 is involved in DNA double-strand break repair. The role of mRtel1 in telomere maintenance...

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Autors principals: Uringa, Evert-Jan, Lisaingo, Kathleen, Pickett, Hilda A., Brind'Amour, Julie, Rohde, Jan-Hendrik, Zelensky, Alex, Essers, Jeroen, Lansdorp, Peter M.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395665/
https://ncbi.nlm.nih.gov/pubmed/22593209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-03-0179
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