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Resolution of telomere associations by TRF1 cleavage in mouse embryonic stem cells

Telomere associations have been observed during key cellular processes such as mitosis, meiosis, and carcinogenesis and must be resolved before cell division to prevent genome instability. Here we establish that telomeric repeat-binding factor 1 (TRF1), a core component of the telomere protein compl...

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Autori principali: Lisaingo, Kathleen, Uringa, Evert-Jan, Lansdorp, Peter M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072570/
https://ncbi.nlm.nih.gov/pubmed/24829382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-10-0564
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