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RTEL1: an essential helicase for telomere maintenance and the regulation of homologous recombination

Telomere maintenance and DNA repair are crucial processes that protect the genome against instability. RTEL1, an essential iron–sulfur cluster-containing helicase, is a dominant factor that controls telomere length in mice and is required for telomere integrity. In addition, RTEL1 promotes synthesis...

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Main Authors: Uringa, Evert-Jan, Youds, Jillian L., Lisaingo, Kathleen, Lansdorp, Peter M., Boulton, Simon J.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061057/
https://ncbi.nlm.nih.gov/pubmed/21097466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1045
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