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Background-free deep imaging by spatial overlap modulation nonlinear optical microscopy

We demonstrate how the resolution and imaging depth limitations of nonlinear optical microscopy can be overcome by modulating the spatial overlap between two-color pulses. We suppress out-of-focus signals, which limit the imaging depth, by a factor of 100, and enhance the lateral and axial resolutio...

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Autori principali: Isobe, Keisuke, Kawano, Hiroyuki, Takeda, Takanori, Suda, Akira, Kumagai, Akiko, Mizuno, Hideaki, Miyawaki, Atsushi, Midorikawa, Katsumi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Optical Society of America 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395484/
https://ncbi.nlm.nih.gov/pubmed/22808431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.3.001594
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