Hyperpolarizing GABAergic Transmission Requires the KCC2 C-Terminal ISO Domain

KCC2 is the neuron-specific member of the of K(+)-Cl(−) cotransporter gene family. It is also the only member of its family that is active under physiologically normal conditions, in the absence of osmotic stress. By extruding Cl(−) from the neuron under isotonic conditions, this transporter maintai...

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Autors principals: Acton, Brooke A., Mahadevan, Vivek, Mercado, Adrianna, Uvarov, Pavel, Ding, Yanli, Pressey, Jessica, Airaksinen, Matti S., Mount, David B., Woodin, Melanie A.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2012
Matèries:
Brief Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395202/
https://ncbi.nlm.nih.gov/pubmed/22723714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6089-11.2012
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