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Hyperpolarizing GABAergic transmission depends on KCC2 function and membrane potential
KCC2 comprises the major Cl(−) extruding mechanism in most adult neurons. Hyperpolarizing GABAergic transmission depends on KCC2 function. We recently demonstrated that glutamate reduces KCC2 function by a phosphorylation-dependent mechanism that leads to excitatory GABA responses. Here we investiga...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3265795/ https://ncbi.nlm.nih.gov/pubmed/22082832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.5.6.17952 |
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