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Tyrosine phosphorylation regulates the membrane trafficking of the potassium chloride co-transporter KCC2
The activity of the neuronal-specific potassium chloride co-transporter KCC2 allows neurons to maintain low intracellular Cl(−) concentrations. These low Cl(−) concentrations are critical in mediating fast synaptic inhibition upon the activation of Cl(−)-permeable ligand-gated ion channels such as t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529177/ https://ncbi.nlm.nih.gov/pubmed/20600929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2010.06.008 |
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