RANK (TNFRSF11A) Is Epigenetically Inactivated and Induces Apoptosis in Gliomas

Alterations of DNA methylation play an important role in gliomas. In a genome-wide screen, we identified a CpG-rich fragment within the 5′ region of the tumor necrosis factor receptor superfamily, member 11A gene (TNFRSF11A) that showed de novo methylation in gliomas. TNFRSF11A, also known as recept...

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Detalhes bibliográficos
Main Authors: von dem Knesebeck, Anna, Felsberg, Jörg, Waha, Anke, Hartmann, Wolfgang, Scheffler, Björn, Glas, Martin, Hammes, Jennifer, Mikeska, Thomas, Yan, Pearlly S, Endl, Elmar, Simon, Matthias, Reifenberger, Guido, Pietsch, Torsten, Waha, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394195/
https://ncbi.nlm.nih.gov/pubmed/22787434
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