Epigenetic Silencing of the Protocadherin Family Member PCDH-γ-A11 in Astrocytomas

In a microarray-based methylation analysis of astrocytomas [World Health Organization (WHO) grade II], we identified a CpG island within the first exon of the protocadherin-γ subfamily A11 (PCDH-γ-A11) gene that showed hypermethylation compared to normal brain tissue. Bisulfite sequencing and combin...

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Bibliografiske detaljer
Main Authors: Waha, Anke, Güntner, Stefanie, Huang, Tim Hui-Ming, Yan, Pearlly S, Arslan, Bülent, Pietsch, Torsten, Wiestler, Otmar D, Waha, Andreas
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press Inc. 2005
Fag:
Brief Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501138/
https://ncbi.nlm.nih.gov/pubmed/15799819
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