Myricetin Inhibits Islet Amyloid Polypeptide (IAPP) Aggregation and Rescues Living Mammalian Cells from IAPP Toxicity

The aggregation of the amyloidogenic polypeptide IAPP (Islet Amyloid Polypeptide, amylin) is believed to play a direct role in the death of pancreatic β-islet cells in type II diabetes. Preventing the initial aggregation event of IAPP is one strategy for slowing, and possibly preventing, the progres...

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Главные авторы: Zelus, Casey, Fox, Ayano, Calciano, Anastasia, Faridian, Bianca S, Nogaj, Luiza A, Moffet, David A
Формат: Artigo
Язык:Inglês
Опубликовано: Bentham Open 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394101/
https://ncbi.nlm.nih.gov/pubmed/22792130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874091X01206010066
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