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Inhibition of Toxic IAPP Amyloid by Extracts of Common Fruits

The aggregation of the 37-amino acid polypeptide islet amyloid polypeptide (IAPP, amylin), as either insoluble amyloid or as small oligomers, appears to play a direct role in the death of pancreatic β-islet cells in type 2 diabetes. It is believed that inhibiting the aggregation of IAPP may slow dow...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Funct Foods
Hauptverfasser: Kao, Pei-Yu, Green, Evangeline, Pereira, Catalina, Ekimura, Shauna, Juarez, Dennis, Whyte, Travis, Arhar, Taylor, Malaspina, Bianca, Nogaj, Luiza A, Moffet, David A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754987/
https://ncbi.nlm.nih.gov/pubmed/26893614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jff.2014.12.013
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