Regulation of PKC-θ function by phosphorylation in T cell receptor signaling

Protein kinase C (PKC)-θ is a serine/threonine kinase belonging to the calcium-independent novel PKC subfamily; its expression is restricted to certain tissues and cell types, including T cells. The signals delivered from T cell receptor (TCR) and CD28 costimulatory molecules trigger PKC-θ catalytic...

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Main Authors: Wang, Xiaohong, Chuang, Huai-Chia, Li, Ju-Pi, Tan, Tse-Hua
格式: Artigo
語言:Inglês
出版: Frontiers Research Foundation 2012
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393885/
https://ncbi.nlm.nih.gov/pubmed/22798961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00197
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