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Homology Modeling and Molecular Dynamics Simulations of the Active State of the Nociceptin Receptor (NOP) Reveals New Insights Into Agonist Binding And Activation
The opioid receptor-like receptor ORL1, also known as the nociceptin receptor (NOP), is a Class A GPCR in the opioid receptor family. Although NOP shares a significant homology with the other opioid receptors, it does not bind known opioid ligands and has been shown to have a distinct mechanism of a...
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| Glavni autori: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3393802/ https://ncbi.nlm.nih.gov/pubmed/22489047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24077 |
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