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Dissecting the Urokinase Activation Pathway Using Urokinase-Activated Anthrax Toxin
Anthrax toxin is a three-part toxin secreted by Bacillus anthracis, consisting of protective antigen (PrAg), edema factor (EF), and lethal factor (LF). To intoxicate host mammalian cells, PrAg, the cell-binding moiety of the toxin, binds to cells and is then proteolytically activated by furin on the...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3393601/ https://ncbi.nlm.nih.gov/pubmed/19377974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60327-003-8_10 |
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