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Dissecting the Urokinase Activation Pathway Using Urokinase-Activated Anthrax Toxin
Anthrax toxin is a three-part toxin secreted by Bacillus anthracis, consisting of protective antigen (PrAg), edema factor (EF), and lethal factor (LF). To intoxicate host mammalian cells, PrAg, the cell-binding moiety of the toxin, binds to cells and is then proteolytically activated by furin on the...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3393601/ https://ncbi.nlm.nih.gov/pubmed/19377974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60327-003-8_10 |
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