CD4(+) CD25(+) Regulatory T Cells Impair HIV-1-Specific CD4 T Cell Responses by Upregulating Interleukin-10 Production in Monocytes

T cell dysfunction in the presence of ongoing antigen exposure is a cardinal feature of chronic viral infections with persistent high viremia, including HIV-1. Although interleukin-10 (IL-10) has been implicated as an important mediator of this T cell dysfunction, the regulation of IL-10 production...

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Detaylı Bibliyografya
Asıl Yazarlar: Kwon, Douglas S., Angin, Mathieu, Hongo, Tomoyuki, Law, Kenneth M., Johnson, Jessica, Porichis, Filippos, Hart, Meghan G., Pavlik, David F., Tighe, Daniel P., Kavanagh, Daniel G., Streeck, Hendrik, Addo, Marylyn M., Kaufmann, Daniel E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2012
Konular:
Pathogenesis and Immunity
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393541/
https://ncbi.nlm.nih.gov/pubmed/22496237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06251-11
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