A Single Amino Acid at the Hemagglutinin Cleavage Site Contributes to the Pathogenicity and Neurovirulence of H5N1 Influenza Virus in Mice

H5 influenza viruses containing a motif of multiple basic amino acids at the hemagglutinin (HA) cleavage site (HACS) are highly pathogenic in chicken but display different virulence phenotypes in mammals. Previous studies have shown that multiple basic amino acids of H5N1 influenza virus are a prere...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Zhang, Yi, Sun, Yipeng, Sun, Honglei, Pu, Juan, Bi, Yuhai, Shi, Yi, Lu, Xishan, Li, Jing, Zhu, Qingyu, Gao, George F., Yang, Hanchun, Liu, Jinhua
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2012
Ämnen:
Pathogenesis and Immunity
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393526/
https://ncbi.nlm.nih.gov/pubmed/22496231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.07142-11
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk