Amino Acid 316 of Hemagglutinin and the Neuraminidase Stalk Length Influence Virulence of H9N2 Influenza Virus in Chickens and Mice

H9N2 influenza viruses with an A316S substitution in hemagglutinin (HA) and a shorter neuraminidase (NA) stalk have become predominant in China. The A316S was shown to increase HA cleavage efficiency when combined with short stalk NA, and the short stalk NA improved NA enzyme activity and release of...

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Detaylı Bibliyografya
Asıl Yazarlar: Sun, Yipeng, Tan, Yuanyuan, Wei, Kai, Sun, Honglei, Shi, Yi, Pu, Juan, Yang, Hanchun, Gao, George F., Yin, Yanbo, Feng, Wenhai, Perez, Daniel R., Liu, Jinhua
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2013
Konular:
Pathogenesis and Immunity
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571412/
https://ncbi.nlm.nih.gov/pubmed/23269805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02688-12
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