A Genetically Engineered Waterfowl Influenza Virus with a Deletion in the Stalk of the Neuraminidase Has Increased Virulence for Chickens

A deletion of about 20 amino acids in the stalk of the neuraminidase (NA) is frequently detected upon transmission of influenza A viruses from waterfowl to domestic poultry. Using reverse genetics, a recombinant virus derived from a wild duck influenza virus isolate, A/Mallard/Marquenterre/Z237/83 (...

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Detalhes bibliográficos
Main Authors: Munier, S., Larcher, T., Cormier-Aline, F., Soubieux, D., Su, B., Guigand, L., Labrosse, B., Cherel, Y., Quéré, P., Marc, D., Naffakh, N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798369/
https://ncbi.nlm.nih.gov/pubmed/19889765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01581-09
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