Draft Genome of Streptomyces tsukubaensis NRRL 18488, the Producer of the Clinically Important Immunosuppressant Tacrolimus (FK506)

The macrocyclic polyketide tacrolimus (FK506) is a potent immunosuppressant that prevents T-cell proliferation produced solely by Streptomyces species. We report here the first draft genome sequence of a true FK506 producer, Streptomyces tsukubaensis NRRL 18488, the first tacrolimus-producing strain...

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Autors principals: Barreiro, Carlos, Prieto, Carlos, Sola-Landa, Alberto, Solera, Elena, Martínez-Castro, Miriam, Pérez-Redondo, Rosario, García-Estrada, Carlos, Aparicio, Jesús F., Fernández-Martínez, Lorena T., Santos-Aberturas, Javier, Salehi-Najafabadi, Zahra, Rodríguez-García, Antonio, Tauch, Andreas, Martín, Juan F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Genome Announcements
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393489/
https://ncbi.nlm.nih.gov/pubmed/22740677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00692-12
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