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FK506 biosynthesis is regulated by two positive regulatory elements in Streptomyces tsukubaensis
BACKGROUND: FK506 (Tacrolimus) is an important immunosuppressant, produced by industrial biosynthetic processes using various Streptomyces species. Considering the complex structure of FK506, it is reasonable to expect complex regulatory networks controlling its biosynthesis. Regulatory elements, pr...
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| Главные авторы: | , , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3551636/ https://ncbi.nlm.nih.gov/pubmed/23083511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-12-238 |
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