FK506 biosynthesis is regulated by two positive regulatory elements in Streptomyces tsukubaensis

BACKGROUND: FK506 (Tacrolimus) is an important immunosuppressant, produced by industrial biosynthetic processes using various Streptomyces species. Considering the complex structure of FK506, it is reasonable to expect complex regulatory networks controlling its biosynthesis. Regulatory elements, pr...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Goranovič, Dušan, Blažič, Marko, Magdevska, Vasilka, Horvat, Jaka, Kuščer, Enej, Polak, Tomaž, Santos-Aberturas, Javier, Martínez-Castro, Miriam, Barreiro, Carlos, Mrak, Peter, Kopitar, Gregor, Kosec, Gregor, Fujs, Štefan, Martín, Juan F, Petković, Hrvoje
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551636/
https://ncbi.nlm.nih.gov/pubmed/23083511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-12-238
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