Annotation of the Modular Polyketide Synthase and Nonribosomal Peptide Synthetase Gene Clusters in the Genome of Streptomyces tsukubaensis NRRL18488

The high G+C content and large genome size make the sequencing and assembly of Streptomyces genomes more difficult than for other bacteria. Many pharmaceutically important natural products are synthesized by modular polyketide synthases (PKSs) and nonribosomal peptide synthetases (NRPSs). The analys...

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Autors principals: Blažič, Marko, Starcevic, Antonio, Lisfi, Mohamed, Baranasic, Damir, Goranovič, Dušan, Fujs, Štefan, Kuščer, Enej, Kosec, Gregor, Petković, Hrvoje, Cullum, John, Hranueli, Daslav, Zucko, Jurica
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Genetics and Molecular Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497360/
https://ncbi.nlm.nih.gov/pubmed/22983969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01891-12
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