dRNA-seq transcriptional profiling of the FK506 biosynthetic gene cluster in Streptomyces tsukubaensis NRRL18488 and general analysis of the transcriptome

FK506 (tacrolimus) is a valuable immunosuppressant produced by several Streptomyces strains. In the genome of the wild type producer Streptomyces tsukubaensis NRRL18488, FK506 biosynthesis is encoded by a gene cluster that spans 83.5 (kb). A whole transcriptome differential shotgun sequencing (dRNA-...

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Dades bibliogràfiques
Publicat a:RNA Biol
Autors principals: Bauer, Judith S., Fillinger, Sven, Förstner, Konrad, Herbig, Alexander, Jones, Adam C., Flinspach, Katrin, Sharma, Cynthia, Gross, Harald, Nieselt, Kay, Apel, Alexander K.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785230/
https://ncbi.nlm.nih.gov/pubmed/28665778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2017.1341020
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