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Mitochondrial respiration protects against oxygen-associated DNA damage

Oxygen is not only required for oxidative phosphorylation but also serves as the essential substrate for the formation of reactive oxygen species (ROS), which is implicated in ageing and tumorigenesis. Although the mitochondrion is known for its bioenergetic function, the symbiotic theory originally...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sung, Ho Joong, Ma, Wenzhe, Wang, Ping-yuan, Hynes, James, O'Riordan, Tomas C., Combs, Christian A., McCoy, J. Philip, Bunz, Fred, Kang, Ju-Gyeong, Hwang, Paul M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393093/
https://ncbi.nlm.nih.gov/pubmed/20975668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1003
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