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Polo-like kinases mediate cell survival in mitochondrial dysfunction

Cancer cells often display defects in mitochondrial respiration, thus the identification of pathways that promote cell survival under this metabolic state may have therapeutic implications. Here, we report that the targeted ablation of mitochondrial respiration markedly increases expression of Polo-...

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Detalhes bibliográficos
Main Authors: Matsumoto, Takumi, Wang, Ping-yuan, Ma, Wenzhe, Sung, Ho Joong, Matoba, Satoaki, Hwang, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732832/
https://ncbi.nlm.nih.gov/pubmed/19706541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904229106
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