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Mitochondrial respiration protects against oxygen-associated DNA damage

Oxygen is not only required for oxidative phosphorylation but also serves as the essential substrate for the formation of reactive oxygen species (ROS), which is implicated in ageing and tumorigenesis. Although the mitochondrion is known for its bioenergetic function, the symbiotic theory originally...

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Detalhes bibliográficos
Main Authors: Sung, Ho Joong, Ma, Wenzhe, Wang, Ping-yuan, Hynes, James, O'Riordan, Tomas C., Combs, Christian A., McCoy, J. Philip, Bunz, Fred, Kang, Ju-Gyeong, Hwang, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393093/
https://ncbi.nlm.nih.gov/pubmed/20975668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1003
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