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The zinc finger transcription factor Zbtb7b (Thpok, cKrox) represses CD8-lineage gene expression in peripheral CD4 T cells

How CD4-CD8 expression is maintained in mature T cells is largely unknown. The present study has examined the role in this process of the zinc finger protein Zbtb7b, a critical factor for the commitment of MHC II-restricted thymocytes to the CD4 lineage, that remains expressed in mature CD4 cells. W...

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Dettagli Bibliografici
Autori principali: Wang, Lie, Wildt, Kathryn F., Castro, Ehydel, Xiong, Yumei, Feigenbaum, Lionel, Tessarollo, Lino, Bosselut, Rémy
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392968/
https://ncbi.nlm.nih.gov/pubmed/19062319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.09.019
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