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The zinc finger transcription factor Zbtb7b (Thpok, cKrox) represses CD8-lineage gene expression in peripheral CD4 T cells
How CD4-CD8 expression is maintained in mature T cells is largely unknown. The present study has examined the role in this process of the zinc finger protein Zbtb7b, a critical factor for the commitment of MHC II-restricted thymocytes to the CD4 lineage, that remains expressed in mature CD4 cells. W...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3392968/ https://ncbi.nlm.nih.gov/pubmed/19062319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.09.019 |
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