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Murine Motor and Behavior Functional Evaluations for Acute 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) Intoxication

Acute intoxication with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induces nigrostriatal neurodegeneration that reflects Parkinson’s disease (PD) pathobiology. The model is commonly used for rodent studies of PD pathogenesis and diagnostics and for developmental therapeutics. However, tests...

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Hlavní autoři: Hutter-Saunders, Jessica A. L., Gendelman, Howard E., Mosley, R. Lee
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392900/
https://ncbi.nlm.nih.gov/pubmed/21431472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-011-9269-4
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