BL-1023 IMPROVES BEHAVIOR AND NEURONAL SURVIVAL IN 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE-INTOXICATED MICE

The therapeutic potential of BL-1023, a chemical combination of L-3,4-dihydroxyphenylalanine (L-DOPA) and γ-amino butyric acid (GABA), was investigated in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) intoxicated mice. Such animals exhibit nigrostriatal degeneration, characteristic of human Pa...

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Detalhes bibliográficos
Main Authors: Saunders, Jessica A. L. Hutter, Kosloski, Lisa M., McMillan, JoEllyn M., Yotam, Nisemblat, Rinat, Tabakman, Mosley, R. Lee, Gendelman, Howard E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070792/
https://ncbi.nlm.nih.gov/pubmed/21320578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2011.02.015
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