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GM-CSF induces neuroprotective and anti-inflammatory responses in 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine intoxicated mice()

Innate and adaptive immune responses can speed nigrostriatal neurodegeneration in Parkinson’s disease (PD). We posit that GM-CSF can attenuate such responses. In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) intoxicated mice, GM-CSF given prior to MPTP protected nigral dopaminergic neurons coi...

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Autors principals: Kosloski, Lisa M., Kosmacek, Elizabeth A., Olson, Katherine E., Mosley, R. Lee, Gendelman, Howard E.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872482/
https://ncbi.nlm.nih.gov/pubmed/24210793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2013.10.009
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