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A computational model for early events in B cell antigen receptor signaling: analysis of the roles of Lyn and Fyn

B cell antigen receptor (BCR) signaling regulates the activities and fates of B cells. BCR signaling encompasses two feedback loops emanating from Lyn and Fyn, which are Src-family protein tyrosine kinases (SFKs). Positive feedback arises from SFK-mediated trans phosphorylation of BCR and receptor-b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Barua, Dipak, Hlavacek, William S., Lipniacki, Tomasz
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392547/
https://ncbi.nlm.nih.gov/pubmed/22711887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102003
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