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A computational model for early events in B cell antigen receptor signaling: analysis of the roles of Lyn and Fyn
B cell antigen receptor (BCR) signaling regulates the activities and fates of B cells. BCR signaling encompasses two feedback loops emanating from Lyn and Fyn, which are Src-family protein tyrosine kinases (SFKs). Positive feedback arises from SFK-mediated trans phosphorylation of BCR and receptor-b...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3392547/ https://ncbi.nlm.nih.gov/pubmed/22711887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102003 |
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