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Stochastic effects and bistability in T cell receptor signaling
The stochastic dynamics of T cell receptor (TCR) signaling are studied using a mathematical model intended to capture kinetic proofreading (sensitivity to ligand-receptor binding kinetics) and negative and positive feedback regulation mediated respectively by the phosphatase SHP1 and the MAP kinase...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2577002/ https://ncbi.nlm.nih.gov/pubmed/18556025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2008.05.001 |
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