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Autocrine IFN-γ promotes naïve CD8 T cell differentiation and synergizes with IFN-α to stimulate strong function()

Autocrine IFN-γ signaling is important for CD4 differentiation to T helper 1 effector cells, but it has been unclear whether it contributes to CD8 T cell differentiation. We show here that naïve murine CD8 T cells rapidly and transiently produce low levels of IFN-γ upon stimulation with Ag and B7-1,...

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Hlavní autoři: Curtsinger, Julie M., Agarwal, Pujya, Lins, Debra C., Mescher, Matthew F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392455/
https://ncbi.nlm.nih.gov/pubmed/22706089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102727
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