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CpG and Interleukin-15 Synergize to Enhance IFN-γ Production by Activated CD8(+) T Cells

Interleukin-15 (IL-15) regulates the development and maintenance of memory CD8(+) T cells. Paradoxically, we previously reported that IL-15 could enhance CD8(+) T-cell responses to IL-12, a proinflammatory cytokine required for optimal priming of effector CD8(+) T cells. To expand the physiological...

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Detalhes bibliográficos
Main Authors: Cobb, Dustin, Guo, Siqi, Smeltz, Ronald B.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591192/
https://ncbi.nlm.nih.gov/pubmed/23509806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/924023
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