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Autocrine IFN-γ promotes naïve CD8 T cell differentiation and synergizes with IFN-α to stimulate strong function()
Autocrine IFN-γ signaling is important for CD4 differentiation to T helper 1 effector cells, but it has been unclear whether it contributes to CD8 T cell differentiation. We show here that naïve murine CD8 T cells rapidly and transiently produce low levels of IFN-γ upon stimulation with Ag and B7-1,...
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| Main Authors: | , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2012
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3392455/ https://ncbi.nlm.nih.gov/pubmed/22706089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102727 |
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