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NMR and crystalstructures of the Pyrococcus horikoshii RadA intein guide a strategy for engineering a highly efficient and promiscuous intein
In protein splicing, an intervening protein sequence (intein) in the host protein excises itself out and ligates two split host protein sequences (exteins) to produce a mature host protein. Inteins require the involvement for the splicing of the first residue of the exteinthat follows the intein (wh...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3392434/ https://ncbi.nlm.nih.gov/pubmed/22560994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.04.029 |
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