Structural basis for the persistence of homing endonucleases in transcription factor IIB inteins

Inteins are mobile genetic elements that are spliced out of proteins after translation. Some inteins contain a homing endonuclease (HEN) responsible for their propagation. Hedgehog/INTein (HINT) domains catalyzing protein splicing and their nested HEN domains are thought to be functionally independe...

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Vydáno v:J Mol Biol
Hlavní autoři: Iwaï, Hideo, Mikula, Kornelia M., Oeemig, Jesper S., Zhou, Dongwen, Li, Mi, Wlodawer, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309676/
https://ncbi.nlm.nih.gov/pubmed/29055778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.10.016
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