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A proteasome inhibitor fails to attenuate dystrophic pathology in mdx mice
Dystrophin deficiency leads to increased proteasome activity in skeletal muscle. Previous observations suggest short-term inhibition of the proteasome restores dystrophin expression. Contrary to our hypothesis, eight days of MG-132 administration to mdx mice increased susceptibility to contraction i...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3392143/ https://ncbi.nlm.nih.gov/pubmed/22866241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/4f84a944d8930 |
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