Aminoimidazole Carboxamide Ribonucleotide Ameliorates Experimental Autoimmune Uveitis

PURPOSE. To investigate the anti-inflammatory effect of an adenosine monophosphate (AMP) analog, aminoimidazole carboxamide ribonucleotide (AICAR), in experimental autoimmune uveoretinitis (EAU). METHODS. C57BL/6 mice were injected daily with AICAR (200 mg/kg, intraperitoneally [IP]) from day 0, the...

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Hlavní autoři: Suzuki, Jun, Yoshimura, Takeru, Simeonova, Marina, Takeuchi, Kimio, Murakami, Yusuke, Morizane, Yuki, Miller, Joan W., Sobrin, Lucia, Vavvas, Demetrios G.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Association for Research in Vision and Ophthalmology 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392008/
https://ncbi.nlm.nih.gov/pubmed/22562518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-9323
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