AMP-activated Protein Kinase Suppresses Matrix Metalloproteinase-9 Expression in Mouse Embryonic Fibroblasts

Matrix metalloproteinase-9 (MMP-9) plays a critical role in tissue remodeling under both physiological and pathological conditions. Although MMP-9 expression is low in most cells and is tightly controlled, the mechanism of its regulation is poorly understood. We utilized mouse embryonic fibroblasts...

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Bibliographic Details
Main Authors: Morizane, Yuki, Thanos, Aristomenis, Takeuchi, Kimio, Murakami, Yusuke, Kayama, Maki, Trichonas, George, Miller, Joan, Foretz, Marc, Viollet, Benoit, Vavvas, Demetrios G.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091212/
https://ncbi.nlm.nih.gov/pubmed/21402702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.199398
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