Evidence for Baseline Retinal Pigment Epithelium Pathology in the Trp1-Cre Mouse

The increasing popularity of the Cre/loxP recombination system has led to the generation of numerous transgenic mouse lines in which Cre recombinase is expressed under the control of organ- or cell-specific promoters. Alterations in retinal pigment epithelium (RPE), a multifunctional cell monolayer...

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Hlavní autoři: Thanos, Aristomenis, Morizane, Yuki, Murakami, Yusuke, Giani, Andrea, Mantopoulos, Dimosthenis, Kayama, Maki, Roh, Mi In, Michaud, Norman, Pawlyk, Basil, Sandberg, Michael, Young, Lucy H., Miller, Joan W., Vavvas, Demetrios G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2012
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349832/
https://ncbi.nlm.nih.gov/pubmed/22429967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.01.017
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