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Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis

Apoptosis has been shown to be a significant form of cell loss in many diseases. Detachment of photoreceptors from the retinal pigment epithelium, as seen in various retinal disorders, causes photoreceptor loss and subsequent vision decline. Although caspase-dependent apoptotic pathways are activate...

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Hlavní autoři: Trichonas, George, Murakami, Yusuke, Thanos, Aristomenis, Morizane, Yuki, Kayama, Maki, Debouck, Christine M., Hisatomi, Toshio, Miller, Joan W., Vavvas, Demetrios G.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003048/
https://ncbi.nlm.nih.gov/pubmed/21098270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009179107
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