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Retinoic acid and liver X receptor agonist synergistically inhibit HIV infection in CD4+ T cells by up-regulating ABCA1-mediated cholesterol efflux

BACKGROUND: Retinoic acids regulate the reverse cholesterol transport by inducing the ATP binding cassette transporter A1 (ABCA1) dependent cholesterol efflux in macrophages, neuronal as well as intestine cells. In the present study, we aim to test the effect of all trans retinoic acid (ATRA) on ABC...

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Detalhes bibliográficos
Main Authors: Jiang, Hong, Badralmaa, Yunden, Yang, Jun, Lempicki, Richard, Hazen, Allison, Natarajan, Ven
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391983/
https://ncbi.nlm.nih.gov/pubmed/22676378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-11-69
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