Antiviral Mechanism and Biochemical Basis of the Human APOBEC3 Family

The human APOBEC3 (A3) family (A, B, C, DE, F, G, and H) comprises host defense factors that potently inhibit the replication of diverse retroviruses, retrotransposons, and the other viral pathogens. HIV-1 has a counterstrategy that includes expressing the Vif protein to abrogate A3 antiviral functi...

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Bibliographic Details
Main Authors: Imahashi, Mayumi, Nakashima, Masaaki, Iwatani, Yasumasa
Format: Artigo
Language:Inglês
Published: Frontiers Research Foundation 2012
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391693/
https://ncbi.nlm.nih.gov/pubmed/22787460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2012.00250
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