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Structural Features of Antiviral APOBEC3 Proteins are Linked to Their Functional Activities

Human APOBEC3 (A3) proteins are cellular cytidine deaminases that potently restrict the replication of retroviruses by hypermutating viral cDNA and/or inhibiting reverse transcription. There are seven members of this family including A3A, B, C, DE, F, G, and H, all encoded in a tandem array on human...

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Bibliografske podrobnosti
Main Authors: Kitamura, Shingo, Ode, Hirotaka, Iwatani, Yasumasa
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Research Foundation 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243911/
https://ncbi.nlm.nih.gov/pubmed/22203821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2011.00258
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