Monomeric APOBEC3G Is Catalytically Active and Has Antiviral Activity

APOBEC3G (APO3G) is a cytidine deaminase that restricts replication of vif-defective human immunodeficiency virus type 1 (HIV-1). Like other members of the cellular deaminase family, APO3G has the propensity to form homo-multimers. In the current study, we investigated the functional determinants fo...

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Detalhes bibliográficos
Main Authors: Opi, Sandrine, Takeuchi, Hiroaki, Kao, Sandra, Khan, Mohammad A., Miyagi, Eri, Goila-Gaur, Ritu, Iwatani, Yasumasa, Levin, Judith G., Strebel, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472092/
https://ncbi.nlm.nih.gov/pubmed/16641260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.10.4673-4682.2006
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