Enzymatically Active APOBEC3G Is Required for Efficient Inhibition of Human Immunodeficiency Virus Type 1

APOBEC3G (APO3G) is a cellular cytidine deaminase with potent antiviral activity. Initial studies of the function of APO3G demonstrated extensive mutation of the viral genome, suggesting a model in which APO3G's antiviral activity is due to hypermutation of the viral genome. Recent studies, how...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Miyagi, Eri, Opi, Sandrine, Takeuchi, Hiroaki, Khan, Mohammad, Goila-Gaur, Ritu, Kao, Sandra, Strebel, Klaus
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2007
Témata:
Cellular Response to Infection
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168852/
https://ncbi.nlm.nih.gov/pubmed/17928335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01361-07
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky