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Interleukin-2 Production by Polyfunctional HIV-1-Specific CD8 T-cells is Associated with Enhanced Viral Suppression

BACKGROUND: Assays to measure the induction of HIV-1-specific CD8 T-cell responses often rely on measurements of indirect effector function such as chemokine and cytokine production, which may not reflect direct elimination of an invading pathogen. Assessment of the functional ability of CD8 T-cells...

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Main Authors: Akinsiku, Olusimidele T., Bansal, Anju, Sabbaj, Steffanie, Heath, Sonya L., Goepfert, Paul A.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391567/
https://ncbi.nlm.nih.gov/pubmed/21637109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e318224d2e9
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