Interleukin-21-Producing HIV-1-Specific CD8 T Cells Are Preferentially Seen in Elite Controllers

A hallmark of human immunodeficiency virus type 1 (HIV-1) pathogenesis is the rapid loss of CD4 T cells leading to generalized immune dysfunction, including an exhausted CD8 T cell phenotype. Understanding the necessary factors that govern the functional quality and protective potential of antiviral...

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Detalhes bibliográficos
Main Authors: Williams, LaTonya D., Bansal, Anju, Sabbaj, Steffanie, Heath, Sonya L., Song, Wei, Tang, Jianming, Zajac, Allan J., Goepfert, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067790/
https://ncbi.nlm.nih.gov/pubmed/21159862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01476-10
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