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Immune Activation Is Associated with CD8 T Cell Interleukin-21 Production in HIV-1-Infected Individuals

Interleukin-21 (IL-21) can be produced by CD8 T cells from HIV-1-infected individuals and those with autoimmune disease, but the mechanism remains poorly understood. Here we demonstrate that IL-21-producing CD8 T cells are not associated with CD4 depletion and are absent in patients with idiopathic...

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Detalhes bibliográficos
Main Authors: Williams, LaTonya D., Amatya, Nilesh, Bansal, Anju, Sabbaj, Steffanie, Heath, Sonya L., Sereti, Irini, Goepfert, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136345/
https://ncbi.nlm.nih.gov/pubmed/24942568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00764-14
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